Theory posits that organizations are embedded socially within their environment. The level of embeddedness depends highly on the environmental uncertainty a company and its network partners face. The latest research on transition economies indicates that the institutional framework in these countries is highly relevant for inter-organizational structures (i.e. formalization, standardization, frequency, intensity and reciprocity). As Russia constitutes a good example of high environmental uncertainty, a closer look at organizational changes in general and inter-organizational network structures in particular is taken. This paper extends the theoretical and empirical scope of social and economic theories on inter-organizational structures by formulating a conceptual framework that unites economic rationalism with socially embedded arguments. Contributing to emerging international HRD literature, the objective is to understand better the institutional influences on network structures and thus on organizational change. Moreover, it will be demonstrated how far organizational changes and human resource development is associated with institutional influences on network structures.