Interrogating the viral dark matter of the rumen ecosystem with a global virome database
The diverse rumen virome can modulate the rumen microbiome, but it remains largely
unexplored. Here, we mine 975 published rumen metagenomes for viral sequences, create
a global rumen virome database (RVD), and analyze the rumen virome for diversity, virus-
host linkages, and potential roles in affecting rumen functions. Containing 397,180 species-
level viral operational taxonomic units (vOTUs), RVD substantially increases the detection
rate of rumen viruses from metagenomes compared with IMG/VR V3. Most of the classified …
unexplored. Here, we mine 975 published rumen metagenomes for viral sequences, create
a global rumen virome database (RVD), and analyze the rumen virome for diversity, virus-
host linkages, and potential roles in affecting rumen functions. Containing 397,180 species-
level viral operational taxonomic units (vOTUs), RVD substantially increases the detection
rate of rumen viruses from metagenomes compared with IMG/VR V3. Most of the classified …
[引用][C] Interrogating the viral dark matter of the rumen ecosystem with a global virome database. Nat Commun 14: 5254
M Yan, AA Pratama, S Somasundaram, Z Li, Y Jiang… - 2023
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