Intraperitoneal administration of plasma-activated medium: proposal of a novel treatment option for peritoneal metastasis from gastric cancer

S Takeda, S Yamada, N Hattori, K Nakamura… - Annals of surgical …, 2017 - Springer
… Although PAM was repeatedly administered intraperitoneally, … PAM treatment inhibits the
formation of peritoneal metastases. … on the effectiveness of intraperitoneally administered PAM. …

Novel intraperitoneal treatment with non-thermal plasma-activated medium inhibits metastatic potential of ovarian cancer cells

K Nakamura, Y Peng, F Utsumi, H Tanaka, M Mizuno… - Scientific reports, 2017 - nature.com
proposed as a new therapeutic tool for cancer treatment. Recently, … to the development of a
new treatment for ovarian cancer. … involving the use of PAM via intraperitoneal administration. …

[HTML][HTML] InvivoPen: A novel plasma source for in vivo cancer treatment

X Zhou, D Cai, S Xiao, M Ning, R Zhou, S Zhang… - Journal of …, 2020 - ncbi.nlm.nih.gov
… CAP treatment is largely achieved using plasma activated … We also proposed that
invivoPen delivered its selective … is 10 mg·ml -1 ) intraperitoneally before each treatment. The …

Plasma-Activated solution in cancer treatment

H Tanaka, M Laroussi, S Bekeschus, D Yan… - … Cancer Therapy, 2020 - Springer
… tissue by subcutaneous or intraperitoneal injection in vivo. To date, the CAP-activated …
the most promising candidates to pursue this promising novel treatment avenue further [55]. …

Preclinical verification of the efficacy and safety of aqueous plasma for ovarian cancer therapy

K Nakamura, N Yoshikawa, Y Mizuno, M Ito, H Tanaka… - Cancers, 2021 - mdpi.com
intraperitoneal administration of plasma-activated solution in a mouse model effectively
suppresses the peritoneal … We propose a new treatment protocol, as indicated in Figure 5a, using …

Current understanding of plasma-activated solutions for potential cancer therapy

N Yoshikawa, K Nakamura, H Kajiyama - Free Radical Research, 2023 - Taylor & Francis
… , and they have been proposed to generate singlet oxygen as … of peritoneal dissemination
of ovarian cancer treated with PAS [… water can be safely injected into the bone marrow of New

Biological and medical applications of plasma-activated media, water and solutions

NK Kaushik, B Ghimire, Y Li, M Adhikari… - Biological …, 2019 - degruyter.com
… plasma has been proposed as a new tool for various … intraperitoneal injection of PAM in a
mouse model. It was concluded that plasma-activated liquids may represent a novel treatment

Effect of plasma-activated lactated ringer's solution on pancreatic cancer cells in vitro and in vivo

Y Sato, S Yamada, S Takeda, N Hattori… - Annals of surgical …, 2018 - Springer
… Furthermore, we evaluated the effect of the intraperitoneal administration of PAL using a
peritonealIntraperitoneal administration of PAL may be a novel therapeutic option for …

Irrigation of peritoneal cavity with cold atmospheric plasma treated solution effectively reduces microbial load in rat acute peritonitis model

MO Oztan, UK Ercan, A Aksoy Gokmen, F Simsek… - Scientific Reports, 2022 - nature.com
… being debated, and novel methods are needed. In the present study, the use of cold plasma
treated saline solution as an intraperitoneal irrigation solution for the management of acute …

The antitumor effects of plasma-activated saline on muscle-invasive bladder cancer cells in vitro and in vivo demonstrate its feasibility as a potential therapeutic …

H Zhang, J Zhang, B Guo, H Chen, D Xu, MG Kong - Cancers, 2021 - mdpi.com
novel treatment strategy for muscle-invasive bladder cancer. … proposed to play major roles
in the anticancer effects [13,38]. … the feasibility of PAS therapy as a novel treatment option for …