Intrarenal purinergic signaling in the control of renal tubular transport
HA Praetorius, J Leipziger - Annual review of physiology, 2010 - annualreviews.org
Renal tubular epithelial cells receive hormonal input that regulates volume and electrolyte
homeostasis. In addition, numerous intrarenal, local signaling agonists have appeared on
the stage of renal physiology. One such system is that of intrarenal purinergic signaling. This
system involves all the elements necessary for agonist-mediated intercellular
communication. ATP is released from epithelial cells, which activates P2 receptors in the
apical and basolateral membrane and thereby modulates tubular transport. Termination of …
homeostasis. In addition, numerous intrarenal, local signaling agonists have appeared on
the stage of renal physiology. One such system is that of intrarenal purinergic signaling. This
system involves all the elements necessary for agonist-mediated intercellular
communication. ATP is released from epithelial cells, which activates P2 receptors in the
apical and basolateral membrane and thereby modulates tubular transport. Termination of …
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