Intrastromal voriconazole for deep recalcitrant fungal keratitis: a case series

G Kalaiselvi, S Narayana, T Krishnan… - British Journal of …, 2015 - bjo.bmj.com
Aim To evaluate the outcomes of treating deep recalcitrant fungal keratitis with intrastromal
voriconazole injection. Methods Twenty-five patients with culture proven fungal keratitis, not
responding to a combination of topical 5% natamycin and 1% voriconazole were treated
with intrastromal voriconazole (50 µg/0.1 mL) injected in five divided doses around the
infiltrate to form a depot of the drug around the circumference of the lesion. Results The
mean age of the patients was 52.52±12.21 years and mean time to presentation was …

Intrastromal voriconazole for deep recalcitrant fungal keratitis: a case series.

GK Ganapathy Kalaiselvi, SN Sivananda Narayana… - 2015 - cabidigitallibrary.org
Aim: To evaluate the outcomes of treating deep recalcitrant fungal keratitis with intrastromal
voriconazole injection. Methods: Twenty-five patients with culture proven fungal keratitis, not
responding to a combination of topical 5% natamycin and 1% voriconazole were treated
with intrastromal voriconazole (50 µg/0.1 mL) injected in five divided doses around the
infiltrate to form a depot of the drug around the circumference of the lesion. Results: The
mean age of the patients was 52.52±12.21 years and mean time to presentation was …
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