Design is a sophisticated cognitive activity that aims at producing creative ideas and products. At the beginning, designers start to navigate the design space to grasp the problem formulation and subsequently identify possible solutions. Design problems are characterized by complexity, unfamiliarity, and ambiguity. That is why the design process is described as a process where ambiguity is progressively resolved. On the other hand, recent studies have argued that the capacity to tolerate ambiguity and work efficiently is about to have ‘negative capability’. Since the process of designing engenders negative feelings especially during experiencing states of not knowing and being stuck; the paper attempts to explore the notion of negative capability and reveal its significance to design thinking. By implementing theoretical research approach, the researchers will adopt inductive logic to explain and understand ambiguity in design reasoning. Hence, the paper discusses theoretical and descriptive materials and uses secondary analysis in order to develop a discourse that designers must have the ability to tolerate ambiguity in order to be more creative designers. By conducting a comprehensive synthesis, the researchers developed a conceptual framework that proposes ways for cultivating negative capability inside the architectural design studio.