Involvement of Na+/H+ exchanger and respiratory burst enzymes NADPH oxidase and NO synthase, in Cd-induced lipid peroxidation and DNA damage in …

E Banakou, S Dailianis - Comparative Biochemistry and Physiology Part C …, 2010 - Elsevier
This study investigated cadmium-induced oxidative and genotoxic effects, such as lipid
peroxidation and disturbance of DNA integrity (DNA damage) in haemocytes of mussel
Mytilus galloprovincialis and the possible involvement of Na+/H+ exchanger (NHE), and/or
the main enzymes of respiratory burst, NADPH oxidase and nitric oxide (NO) synthase, in
the induction of Cd toxic effects. In order to verify the role of either NHE, or NADPH oxidase
and NO synthase in Cd-mediated toxicity, inhibitors such as ethyl-N-isopropyl-amiloride …
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