Laparoscopic Gastric Sleeve (LGS) become one of the most implemented bariatric procedures globally. Nevertheless, iron deficiency is one of the most common nutritional deficiencies in general, and in patients with obesity, particularly following bariatric surgeries. Several health recommendations worldwide urged for the effectiveness of iron supplementation after bariatric surgeries. Short term and long-term data on iron anemia deficiency after LGS are generally lacking. This study aimed to examine the effect within (3 months, 6 months, 1 year, 2 years and 5 years) on iron deficiency in patients with obesity who underwent LGS operation.

Cohort Retrospective observational study design for 5 years follow up, from 2015 to 2020. The study was used unidentified recorded data from the hospital of 863 patients with obesity who underwent LGS with/without a history of iron deficiency anemia as operation day as a baseline point, within 3 months, 6 months, 12 months, 2 years, and 5 years postoperatively.

the results showed that the average value of serum iron before surgery was 62.32 ug/dl, then the mean value had slightly decreased during the first three months of operation. Then, the mean value of iron slightly increased from 3 months up to 12 months, postoperatively. After 1 year up to 5 years, postoperatively, the mean value of iron again slightly decreased to reach 52.60 ug/dl.

LGS, as an effective and common bariatric surgery method, does not significantly affect the levels of serum iron, during 5 years postoperatively in patients with obesity, with or without iron anemia deficiency.