Since its initial description, there have been significant changes in the epidemiology,
pathogenesis, and clinical and imaging manifestations of JCV infection of brain. The most common …

… a demyelinating disorder of the human brain caused by infection with the human polyomavirus,
JC. Up to 80% of humans express serum antibodies to JC virus (JCV), yet considerably …

… disease in the human brain in which the basis for … JC virus (JCV), which causes lytic infection
of the myelin-producing oligodendrocyte. Although the simian polyomavirus simian virus 40 …

… The molecular biology of JC virus, causative of papova-like virus from human brain with …
region of BK and JC Induction of brain tumors by a newly isolated JC virus (Tokyo-1 strain). …

… Detection of BK virus and JC virus in urine and brain tissue … Occurrence and significance
of papovaviruses BK and JC in … Involvement of JC virus-infected mononuclear cells from the …

… JC virus (JCV) is the etiologic agent of the often fatal brain-… cause a lytic infection of
oligodendrocytes in the brain, leading to … leading to viral reactivation and replication in the brains …

… polyomavirus JC, JC virus (JCV) is well known for causing progressive multifocal
leukoencephalopathy(PML) 1 , an often lethal disease of the brain resulting from lytic infection of glial …

… The etiological agent of PML was not isolated until 1971, when the virus was isolated from
a … JC virus (JCV), after the initials of the patient. More recently, JCV has been termed JC …

… Infection was also demonstrated by JCV qPCR in the virus-exposed organoids and their
media. In conclusion, the brain organoid model of JCV infection … of JCV infection and …

… late proteins in five distinct areas of brains from non-PML immunocompetent … viral DNA are
detectable in various regions of the brain, no viral proteins are expressed in the normal brain. …