Jejunal perforation: a rare presentation of B-cell lymphoma

V Santharam, P Kumar, LYW Lee - Case Reports, 2014 - casereports.bmj.com
V Santharam, P Kumar, LYW Lee
Case Reports, 2014casereports.bmj.com
A 42-year-old man who was being treated for pneumonia developed severe, sudden-onset
abdominal pain with features of shock and peritonism. The clinical picture combined with
radiological investigations raised suspicion of a bowel perforation necessitating urgent
surgical review and emergency laparotomy. This diagnosed a jejunal perforation with
abnormal lymph nodes. Histological examination confirmed diffuse large B-cell lymphoma.
The patient was subsequently started on a course of chemotherapy. While gastrointestinal …
Summary
A 42-year-old man who was being treated for pneumonia developed severe, sudden-onset abdominal pain with features of shock and peritonism. The clinical picture combined with radiological investigations raised suspicion of a bowel perforation necessitating urgent surgical review and emergency laparotomy. This diagnosed a jejunal perforation with abnormal lymph nodes. Histological examination confirmed diffuse large B-cell lymphoma. The patient was subsequently started on a course of chemotherapy. While gastrointestinal perforation secondary to antilymphoma treatment is a well-recognised complication, primary perforation caused by the lymphoma itself must always be considered.
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