Kinin receptors in cultured rat microglia

M Noda, Y Kariura, T Amano, Y Manago… - Neurochemistry …, 2004 - Elsevier
… The presence of bradykinin receptors in microglia has been of great significance. … rat
primary microglia express kinin receptors. In resting microglia, B 2 receptors but not B 1 receptors

Anti-inflammatory effects of kinins via microglia in the central nervous system

M Noda, H Kettenmann, K Wada - 2006 - degruyter.com
… Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing
lipopolysaccharide-induced interleukin-1b … Kinin receptors in cultured rat microglia. Neurochem. …

Expression and function of bradykinin receptors in microglia

M Noda, Y Kariura, T Amano, Y Manago, K Nishikawa… - Life sciences, 2003 - Elsevier
… These results suggest that microglia express B 2 receptors and presumably increase the …
that microglia express functional BK receptors and support the idea that microglia play an …

Inhibitory role of kinins on microglial nitric oxide and tumor necrosis factor-α production

BS Sarit, G Lajos, D Abraham, A Ron, FB Sigal - Peptides, 2012 - Elsevier
… The aim of the present study was to investigate the effects of several kinin receptors agonists
on the release of pro-inflammatory mediators (NO and TNF-α) from a murine microglial cell …

Neuroprotective role of bradykinin because of the attenuation of pro‐inflammatory cytokine release from activated microglia

M Noda, Y Kariura, U Pannasch… - Journal of …, 2007 - Wiley Online Library
receptors and EP2/EP4 receptorsreceptors not only in culture, but also in microglia
from acute brain slices. BK reduced LPS‐induced neuronal death in neuron–microglia co‐cultures. …

Involvement of the Bradykinin B1 Receptor in Microglial Activation: In Vitro and In Vivo Studies

K Asraf, N Torika, A Danon… - Frontiers in …, 2017 - frontiersin.org
… as kinins, can regulate brain inflammation and affect microglial functions both in vitro and
in vivo (14, 15). Thus, the release of these factors can determine whether microglia assume a …

The relevance of kalikrein-kinin system via activation of B2 receptor in LPS-induced fever in rats

D de Melo Soares, DR Santos, C Rummel, D Ott… - …, 2017 - Elsevier
… Single microglial cell responded to a concentration of 5.5 … kinin receptors, the rat CNS
contains all components of kallikrein-kinin system including precursors (kininogens), forming kinin

Key role for spinal dorsal horn microglial kinin B1receptor in early diabetic pain neuropathy

S Talbot, E Chahmi, JP Dias, R Couture - Journal of neuroinflammation, 2010 - Springer
rat. This study aims at defining the role of microglial kinin B 1 R in diabetic pain neuropathy.
… role played by spinal dorsal horn microglial kinin B 1 R in a classical rat model of diabetes-…

Activation of TRPV1 by capsaicin induces functional Kinin B1 receptor in rat spinal cord microglia

S Talbot, JP Dias, K Lahjouji, MR Bogo… - Journal of …, 2012 - Springer
kinin B 1 receptor (B 1 R) is upregulated by pro-inflammatory cytokines and oxydative stress,
which are enhanced by transient receptor … of TRPV1 to regulate microglial B 1 R expression …

Kinins and microglial responses in bipolar disorder: a neuroinflammation hypothesis

YM Naaldijk, MC Bittencourt, U Sack, H Ulrich - Biological chemistry, 2016 - degruyter.com
… for would be BD progression, in which microglia activation states modulated via constitutive
induction of kinin-B1 receptor and reduction of kinin-B2 receptor expression and activity. …