… role of Kupffer cells in metabolic liver diseases and then summarize data demonstrating
that Kupffer cells are protective in other types of liver injury, such as drug-induced liver injury …

… Carl von Kupffer and a scanning electron micrograph demonstrating a Kupffer cell (KC) from
rat liver. Because activated cells appear ruffled (K), Carl von Kupffer called them sternzellen …

… Kupffer cells, the resident liver macrophages have long been considered as mostly scavenger
cells … However, evidence derived mostly from animal models, indicates that Kupffer cells …

… new information regarding the quite versatile functions of Kupffer cells. Although their main
function is phagocytosis and defence of the liver against bacteria, endotoxaemia and viral …

… Results showed that liver regeneration was delayed after Kupffer cell-depletion. In control
… liver regeneration and expressions of HGF were localized in fat-storing cells (Ito cells). In …

… Kupffer cells (KCs) are known as liver-derived macrophages and account for 20–35% of all
non-parenchymal cells in the liver and 80–90% of tissue macrophages present in the body (…

… of the liver (3, 5). In situations where Kupffer cells are nonfunctional, liver endothelial cells
can … The lipid composition of the cellular membrane is a critical factor in phagocytosis. Both …

… liver and comprises sinusoidal endothelial cells, Kupffer cells, … , Kupffer cells of donor origin
repopulate the recipient livers … In transplanted human livers, donor Kupffer cells persist for up …

… of activation and functions of Kupffer cells, followed by hepatic inflammation and … Kupffer
cell studies in cholestatic liver injury. Kupffer cells are tissue-resident macrophages in the liver. …

… These functions of Kupffer cells need rigorous control to avoid escalation of the inflammatory
response. Liver damage may either result from inability of Kupffer cells to properly …