Label-free quantitative analysis of lipid metabolism in living Caenorhabditis elegans [S]

TT Le, HM Duren, MN Slipchenko, CD Hu… - Journal of lipid …, 2010 - ASBMB
The ubiquity of lipids in biological structures and functions suggests that lipid metabolisms
are highly regulated. However, current invasive techniques for lipid studies prevent
characterization of the dynamic interactions between various lipid metabolism pathways.
Here, we describe a noninvasive approach to study lipid metabolisms using a
multifunctional coherent anti-Stokes Raman scattering (CARS) microscope. Using living
Caenorhabditis elegans as a model organism, we report label-free visualization of …
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