Lead acetate induces hippocampal pyramidal neuron degeneration in mice via up-regulation of executioner caspase-3, oxido-inflammatory stress expression and …
Purpose It has been hypothesized that compounds with strong anti-oxidant activity might
mitigate lead-induced neurotoxicity that resulted to neuronal degeneration. Ginkgo biloba
supplement (GB-S) is a neuroactive supplement which has been reported to demonstrate
neuroprotective effects. In this study, we investigated the reversal effect and the underlying
mechanism of GB-S following lead-induced neurotoxicity in mice. Methods Male Swiss mice
(n= 8) were pre-treated with lead acetate (100 mg/kg) for 30 min before GB-S (10 mg/kg and …
mitigate lead-induced neurotoxicity that resulted to neuronal degeneration. Ginkgo biloba
supplement (GB-S) is a neuroactive supplement which has been reported to demonstrate
neuroprotective effects. In this study, we investigated the reversal effect and the underlying
mechanism of GB-S following lead-induced neurotoxicity in mice. Methods Male Swiss mice
(n= 8) were pre-treated with lead acetate (100 mg/kg) for 30 min before GB-S (10 mg/kg and …
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