Lens regeneration using endogenous stem cells with gain of visual function

H Lin, H Ouyang, J Zhu, S Huang, Z Liu, S Chen… - Nature, 2016 - nature.com
The repair and regeneration of tissues using endogenous stem cells represents an ultimate
goal in regenerative medicine. To our knowledge, human lens regeneration has not yet
been demonstrated. Currently, the only treatment for cataracts, the leading cause of
blindness worldwide, is to extract the cataractous lens and implant an artificial intraocular
lens. However, this procedure poses notable risks of complications. Here we isolate lens
epithelial stem/progenitor cells (LECs) in mammals and show that Pax6 and Bmi1 are …

Corrigendum: Lens regeneration using endogenous stem cells with gain of visual function

H Lin, H Ouyang, J Zhu, S Huang, Z Liu, S Chen… - Nature, 2017 - go.gale.com
In this Article, errors in the length of the scale bars were inadvertently introduced into Fig. 3e
and Extended Data Fig. 7b. The corrected Fig. 3e is shown as Fig. 1 of this Corrigendum and
the corrected Extended Data Fig. 7b is shown in the Supplementary Information to this
Corrigendum (both of the corrected scale bars are now shorter).Also, the molecular weight
markers (red rectangles) in Supplementary Fig. 1 (which gives the original gels for Fig. 2,
showing the blot assessing the A-cry, b-cry, g-cry and b-actin proteins) were erroneously …
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