[PDF][PDF] Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics

JJ Partanen, P Häppölä, W Zhou, AA Lehisto, M Ainola… - Cell genomics, 2022 - cell.com
The research of rare and devastating orphan diseases, such as idiopathic pulmonary
fibrosis (IPF) has been limited by the rarity of the disease itself. The prognosis is poor—the
prevalence of IPF is only approximately four times the incidence, limiting the recruitment of
patients to trials and studies of the underlying biology. Global biobanking efforts can
dramatically alter the future of IPF research. We describe a large-scale meta-analysis of IPF,
with 8,492 patients and 1,355,819 population controls from 13 biobanks around the globe …

Leveraging global multi-ancestry meta-analysis in the study of Idiopathic Pulmonary Fibrosis genetics

L Wain - 2022 - figshare.le.ac.uk
The research of rare and devastating orphan diseases, such as idiopathic pulmonary
fibrosis (IPF) has been limited by the rarity of the disease itself. The prognosis is poor—the
prevalence of IPF is only approximately four times the incidence, limiting the recruitment of
patients to trials and studies of the underlying biology. Global biobanking efforts can
dramatically alter the future of IPF research. We describe a large-scale meta-analysis of IPF,
with 8,492 patients and 1,355,819 population controls from 13 biobanks around the globe …
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