[HTML][HTML] Lineage specific trimethylation of H3 on lysine 4 during C. elegans early embryogenesis
S Wang, K Fisher, GB Poulin - Developmental biology, 2011 - Elsevier
In many organisms early embryogenesis is characterised by a period refractory to
transcription. In Caenorhabditis elegans, the one-cell embryo is transcriptionally inactive, but
at around eight-cell stage transcription is activated in the somatic lineage. This model
suggests that histone tail modifications associated with activation of transcription, such as di-
or trimethylation of histone 3 on lysine 4 (H3K4me2/me3) should be enriched in the somatic
lineage. Here, we have investigated the deposition of H3K4me3 during embryogenesis and …
transcription. In Caenorhabditis elegans, the one-cell embryo is transcriptionally inactive, but
at around eight-cell stage transcription is activated in the somatic lineage. This model
suggests that histone tail modifications associated with activation of transcription, such as di-
or trimethylation of histone 3 on lysine 4 (H3K4me2/me3) should be enriched in the somatic
lineage. Here, we have investigated the deposition of H3K4me3 during embryogenesis and …
Lineage specific trimethylation of H3 on lysine 4 during C. elegans early embryogenesis.
WSY Wang SiYao, K Fisher, GB Poulin - 2011 - cabidigitallibrary.org
In many organisms early embryogenesis is characterised by a period refractory to
transcription. In Caenorhabditis elegans, the one-cell embryo is transcriptionally inactive, but
at around eight-cell stage transcription is activated in the somatic lineage. This model
suggests that histone tail modifications associated with activation of transcription, such as di-
or trimethylation of histone 3 on lysine 4 (H3K4me2/me3) should be enriched in the somatic
lineage. Here, we have investigated the deposition of H3K4me3 during embryogenesis and …
transcription. In Caenorhabditis elegans, the one-cell embryo is transcriptionally inactive, but
at around eight-cell stage transcription is activated in the somatic lineage. This model
suggests that histone tail modifications associated with activation of transcription, such as di-
or trimethylation of histone 3 on lysine 4 (H3K4me2/me3) should be enriched in the somatic
lineage. Here, we have investigated the deposition of H3K4me3 during embryogenesis and …