LncRNA BLAT1 is upregulated in basal-like breast cancer through epigenetic modifications

YJ Han, SM Boatman, J Zhang, XC Du, AC Yeh… - Scientific reports, 2018 - nature.com
… , BLAT1 expression is regulated at the epigenetic level via DNA … BLAT1 hypomethylation
showed decreased overall survival. Our results suggest that increased expression of BLAT1 via

Regulation of breast cancer progression by noncoding RNAs

RL Akshaya, M Rohini… - Current Cancer Drug …, 2020 - ingentaconnect.com
… the increased expression of a lncRNA basal-like breast cancer-associated transcript 1 (…
LncRNA BLAT1 is upregulated in basal-like breast cancer through epigenetic modifications. …

[HTML][HTML] lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment

H Jin, W Du, W Huang, J Yan, Q Tang, Y Chen… - … Therapy-Nucleic Acids, 2021 - cell.com
… in breast cancer. Additionally, we also highlight the advantages and challenges of using
lncRNAs as biomarkers for diagnosis or therapeutic targets for drug resistance in breast cancer

Emerging roles of long noncoding RNAs in breast cancer epigenetics and epitranscriptomics

E Wanowska, K Samorowska… - Frontiers in Cell and …, 2022 - frontiersin.org
lncRNAs, Basal-Like breast cancer Associated Transcript 1 (BLAT1) and highly upregulated
… One possibility is to employ lncRNAs and lncRNA-mediated epigenetic modifications, …

Underexplored reciprocity between genome-wide methylation status and long non-coding RNA expression reflected in breast cancer research: potential impacts for …

A Kapinova, A Mazurakova, E Halasova, Z Dankova… - EPMA Journal, 2023 - Springer
into metastatic BC. DNA and histones methylations, as the most studied epigenetic modifications,
… To this end, long non-coding RNAs (lncRNAs) are recognized as potent epigenetic

Emerging patterns and implications of breast cancer epigenetics: an update of the current knowledge

T Venkatesh, S Thankachan, SP Kabekkodu… - Epigenetics and …, 2021 - Elsevier
… of epigenetic alterations and dysregulated genes expression in … lncRNA in association with
epigenetic changes in breast … phenotype of basal-like breast cancer [51]. Recent research …

New insights into long non-coding RNAs in breast cancer: Biological functions and therapeutic prospects

MQ Wang, WJ Zhu, P Gao - Experimental and Molecular Pathology, 2021 - Elsevier
lncRNAs in breast cancer. In the nucleus, lncRNAs can mediate a variety of epigenetic
modification … HOTAIR, one of the most common lncRNAs upregulated in BC, indirectly regulates a …

LncRNA RP11-19E11 is an E2F1 target required for proliferation and survival of basal breast cancer

A Giro-Perafita, L Luo, A Khodadadi-Jamayran… - … Breast Cancer, 2020 - nature.com
… -associated lncRNA, RP11-19E11.1, which is upregulated in … .1 as a specific basal-like
transcript in an independent cohort … this lncRNA was regulated through epigenetic modifications, …

Functional interplay between long non-coding RNAs and Breast CSCs

BM Hussen, RK Kheder, ST Abdullah, HJ Hidayat… - Cancer Cell …, 2022 - Springer
… findings that focus on lncRNAs affect cancer stem cell self-… They showed that cancer patients
with tumors that are BLAT1… by altering the balance of histone modifications on the miR-205 …

Mutual interaction of lncRNAs and epigenetics: Focusing on cancer

M Ranjbar, S Heydarzadeh, M Shekari Khaniani… - Egyptian Journal of …, 2023 - Springer
… methylation/histone modification enzymes mediated by lncRNAs can … Basal-like breast
cancer Associated Transcript-1 (BLAT1) lncRNA is significantly upregulated in Basal-like breast