Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic area of Brazil (Sao Goncalo do Amarante, RN)
GP Borja-Cabrera, NNC Pontes, VO Da Silva… - Vaccine, 2002 - Elsevier
Naturally exposed dogs of an endemic area were vaccinated with the fucose mannose
ligand (FML) antigen of Leishmania donovani in formulation with QuilA saponin. The 100%
of vaccinees were seropositive to FML and showed intradermal reaction to L. donovani
lysate, 2 months after vaccination. The absorbency values and size of intradermal reaction
were both significantly higher in vaccinees than in controls along a 3.5 years period
(ANOVA, P< 0.0001). The 25% of the control animals (two dogs on the first year and six dogs …
ligand (FML) antigen of Leishmania donovani in formulation with QuilA saponin. The 100%
of vaccinees were seropositive to FML and showed intradermal reaction to L. donovani
lysate, 2 months after vaccination. The absorbency values and size of intradermal reaction
were both significantly higher in vaccinees than in controls along a 3.5 years period
(ANOVA, P< 0.0001). The 25% of the control animals (two dogs on the first year and six dogs …
[引用][C] Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic area of Brazil (Sao Goncalo do Amarante RN)
BC GP - Vaccine, 2002 - cir.nii.ac.jp
Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an
endemic area of Brazil (Sao Goncalo do Amarante RN) | CiNii Research … Long lasting
protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic
area of Brazil (Sao Goncalo do Amarante RN) … Vaccine 20 (27), 3277-3284, 2002 …
endemic area of Brazil (Sao Goncalo do Amarante RN) | CiNii Research … Long lasting
protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic
area of Brazil (Sao Goncalo do Amarante RN) … Vaccine 20 (27), 3277-3284, 2002 …
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