Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms
We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell
responses, soluble markers of inflammation, and antibody levels and neutralization capacity
longitudinally in 70 individuals with PCR-confirmed SARS-CoV-2 infection. Participants
represent a spectrum of illness and recovery, including some with persistent viral shedding
in saliva and many experiencing post-acute sequelae of SARS-CoV-2 infection (PASC). T
cell responses remain stable for up to 9 months. Whereas the magnitude of early CD4+ T …
responses, soluble markers of inflammation, and antibody levels and neutralization capacity
longitudinally in 70 individuals with PCR-confirmed SARS-CoV-2 infection. Participants
represent a spectrum of illness and recovery, including some with persistent viral shedding
in saliva and many experiencing post-acute sequelae of SARS-CoV-2 infection (PASC). T
cell responses remain stable for up to 9 months. Whereas the magnitude of early CD4+ T …
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