Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia

CS Tam, S O'Brien, W Wierda… - Blood, The Journal …, 2008 - ashpublications.org
… of remissions and the impact of treatment on overall … long-term outcome of the FCR regimen
at a median follow up of 6 years. These results establish FCR as the most effective regimen

Long-term results of first salvage treatment in CLL patients treated initially with FCR (fludarabine, cyclophosphamide, rituximab)

CS Tam, S O'Brien, W Plunkett… - Blood, The Journal …, 2014 - ashpublications.org
… During the study period, there was no protocol-mandated salvage strategy for patients in …
outcomes of the individual salvage regimens were found to be similar on survival analysis. …

Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia

PA Thompson, CS Tam, SM O'Brien… - Blood, The Journal …, 2016 - ashpublications.org
original study, at a median of 12.8 years posttreatment, with a focus on identifying groups of
patients likely to achieve very long-term … -M had a highly favorable outcome following primary …

Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial

M Hallek, K Fischer, G Fingerle-Rowson, AM Fink… - The Lancet, 2010 - thelancet.com
… On the basis of promising results that were reported in … rituximab to first-line chemotherapy
with fludarabine and … involved in the first and second amendments of the study protocol. The …

Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia

MJ Keating, S O'Brien, M Albitar, S Lerner… - Journal of clinical …, 2005 - ascopubs.org
… the possibility that the use of such regimens may translate into an improved prognosis. …
to confirm the effect of the addition of rituximab to FC. Long-term follow-up of the effect of flow …

First-line chemoimmunotherapy with bendamustine and rituximab versus fludarabine, cyclophosphamide, and rituximab in patients with advanced chronic lymphocytic …

B Eichhorst, AM Fink, J Bahlo, R Busch… - The lancet …, 2016 - thelancet.com
… (250 mg/m 2 per day) for the first 3 days or to intravenous … However, this regimen is associated
with substantial toxic effects, … A long-term follow-up of patients treated with fludarabine, …

Efficacy and longterm toxicity of the rituximabfludarabinecyclophosphamide combination therapy in Waldenstrom's macroglobulinemia

L Souchet, V Levy, M Ouzegdouh… - American journal of …, 2016 - Wiley Online Library
… that RFC is a very effective regimen for relapsed/refractory patients. … Our study is the first to
use the oral route for fludarabine and … Our results cannot be compared with those of the Italian …

… with fludarabine and rituximab produces extended overall survival and progression-free survival in chronic lymphocytic leukemia: long-term follow-up of CALGB study …

JA Woyach, AS Ruppert, NA Heerema… - Journal of Clinical …, 2011 - ascopubs.org
… , and impact of genomic risk factors has been limited. … these fludarabine and cyclophosphamide
combination regimens has … of the first chemoimmunotherapy protocols initiated in which …

… therapy with rituximab leads to a significant prolongation of response duration after salvage therapy with a combination of rituximab, fludarabine, cyclophosphamide …

R Forstpointner, M Unterhalt, M Dreyling, HP Böck… - Blood, 2006 - ashpublications.org
initial therapy but were randomized by violating the protocol. However, in all randomized
patients, the progression-free survival after initial … show a highly beneficial long-term effect of R …

Long-term outcomes to fludarabine and rituximab in Waldenström macroglobulinemia

SP Treon, AR Branagan, L Ioakimidis… - Blood, The Journal …, 2009 - ashpublications.org
… had received cyclophosphamide followed by rituximab. Among … bleed after the first 4 weekly
infusions of rituximab. Byrd et al … and rituximab are an active regimen in WM, although the …