Rationale and objectives Myxofibrosarcoma (MFS) is a common soft tissue sarcoma in the
elderly patients with both clinical and magnetic resonance imaging (MRI) peculiar features:
very high recurrence rate, relatively low risk of distant metastases. On MRI it shows an
infiltrative pattern (“tail sign”) and high myxoid matrix content with water-like appearance on
fluid-sensitive sequences. Due to these unusual characteristics, we propose a specific MRI
grading system to stratify the risk of local recurrence (LR) and offer other prognostic …