… To find out whether nail development in Msx1 mutant mice was affected, we analyzed the
distal limbs of E16.5 and E18.5 wild-type and Msx1 knockout embryos. In E16.5 wild-type …

… has not been reported in any case report of the Witkop syndrome yet. We were, therefore, …
of Coffin-Lowry syndrome. Our next differential diagnosis was the Witkop syndrome in light of …

… The MSX1 mutation is observed in Pierre-Robin sequence. The mutations may lead to Witkop
syndrome or Wolf-Hirschorn syndrome. Further research is required to establish the exact …

… A nonsense mutation in the MSX1 gene with an autosomal dominant pattern … syndrome
(Hudson and Witkop 1975; Jumlongras et al. 2001; Altug-Atac and Iseri 2008). MSX1 mutations …

… gene can also cause syndromic forms of tooth agenesis, including Wolf-Hirschhorn syndrome,
Witkop syndrome, and tooth agenesis combined with orofacial clefting (Table 3). The Wolf-…

… Mutation in MSX-1 has been shown to be associated with Witkop syndrome. This MSX is
recognized to … Des mutations en MSX-1 ont été identifiées dans le syndrome dent et ongle de …

… Mutations in the MSX1 gene result in Witkop's disease. The MSX1 gene is also mutated in
familial tooth agenesis with or without cleft lip/palate, demonstrating that the MSX1 gene is …

… the presence of an Msx1 mutation. In contrast, patients with Pax9 mutations typically show
… to spot the gene and the type of mutation responsible for Witkop syndrome which led to the …

… mutations, such as missense or frame-shift mutations, have been reported to be associated
with tooth agenesis. In the present study, we sequenced the MSX1 … -frame of the MSX1 gene, …