… , pathways regulating lipid homeostasis in macrophages are updated. These include lipid
influx … lipid storage leading to phospholipidosis, and lipid droplet accumulation or activation of …

… have been implicated in the pathogenesis of several diseases in which lipid homeostasis
is perturbed such as atherosclerosis, non-alcoholic fatty liver disease (NAFLD) and alveolar …

… Lipid handling by tissue macrophages. A The metabolism of alveolar macrophages present
in lung tissue is specialized for lipid catabolism and trafficking for effective clearance of …

… immunity against microbes. Thus, the initial concept of macrophages promoting “balance” in
the host (homeostasis) was … family of lipid mediators that contribute to the homeostatic role of …

… metabolism, including lipid metabolism. Here, we review how macrophage lipid metabolism
can … , tissue homeostasis, and host defense, while aberrant lipid metabolism contributes to …

… , there has been great interest on the effect of lipids on macrophage function and activation.
Macrophages take up lipids via scavenger receptors, such as CD36 and scavenger receptor …

… map all adipose tissue immune populations in both mice and … and conserved Trem2 +
lipid-associated macrophage (LAM) … by which macrophages respond to loss of tissue-level lipid …

… nature of apoptotic cell interaction with the immune system. We do not … in macrophages
and DCs that are related to toll-like receptors, nuclear factor kappa B, inflammasome, the lipid-…

… macrophage homeostasis. PPARs and LXRs control transcriptional programs involved in
processes of lipid … the context of macrophage lipid homeostasis and the control of inflammation. …

… failure to maintain local lipid homeostasis and long-term effects on immune cells beyond the
… homeostasis and metabolic inflammation. Additionally, we hypothesize that trained immunity…