In the investigation of ischemic stroke, conventional structural magnetic resonance (MR)
techniques (eg, T1-weighted imaging, T2-weighted imaging, and proton density-weighted
imaging) are valuable for the assessment of infarct extent and location beyond the first 12 to
24 hours after onset, and can be combined with MR angiography to noninvasively assess
the intracranial and extracranial vasculature. However, during the critical first 6 to 12 hours,
the probable period of greatest therapeutic opportunity, these methods do not adequately …

Stroke is a common and serious disorder, with an annual incidence of approximately
795,000 in the United States, of which approximately 85% are ischemic and 15% are
hemorrhagic. 1 Neuroimaging plays a critical role in the diagnosis and management of
patients with acute stroke. The neuroimaging evaluation of patients with suspected acute
stroke has significantly evolved over the past few decades from a simple noncontrast
computed tomography (CT) to now frequently including multiparametric data, including …