The optimal management of severe traumatic brain injury (TBI) in the pediatric population
has not been well studied. There are a limited number of research articles studying the
management of TBI in children. Given the prevalence of severe TBI in the pediatric
population, it is crucial to develop a reference TBI management plan for this vulnerable
population. In this review, we seek to delineate the differences between severe TBI
management in adults and children. Additionally, we also discuss the known molecular …

Background Traumatic brain injury (TBI) is a major cause of death and disability worldwide.
The decision-making process in the management of severe TBI must be based on the best
available evidence to minimize the occurrence of secondary brain injuries. However,
healthcare approaches to managing TBI patients exhibit considerable variation. Methods
Over an 18-month period, a multidisciplinary panel consisting of medical doctors,
physiotherapists, nutritional therapists, and nurses performed a comprehensive review on …