Manganese co-localizes with calcium and phosphorus in Chlamydomonas acidocalcisomes and is mobilized in manganese-deficient conditions
Exposing cells to excess metal concentrations well beyond the cellular quota is a powerful
tool for understanding the molecular mechanisms of metal homeostasis. Such improved
understanding may enable bioengineering of organisms with improved nutrition and
bioremediation capacity. We report here that Chlamydomonas reinhardtii can accumulate
manganese (Mn) in proportion to extracellular supply, up to 30-fold greater than its typical
quota and with remarkable tolerance. As visualized by X-ray fluorescence microscopy and …
tool for understanding the molecular mechanisms of metal homeostasis. Such improved
understanding may enable bioengineering of organisms with improved nutrition and
bioremediation capacity. We report here that Chlamydomonas reinhardtii can accumulate
manganese (Mn) in proportion to extracellular supply, up to 30-fold greater than its typical
quota and with remarkable tolerance. As visualized by X-ray fluorescence microscopy and …
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