[HTML][HTML] Manufacturing and characterization of extracellular vesicles from umbilical cord–derived mesenchymal stromal cells for clinical testing
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) may deliver
therapeutic effects that are comparable to their parental cells. MSC-EVs are promising
agents for the treatment of a variety of diseases. To reach the intermediate goal of clinically
testing safety and efficacy of EVs, strategies should strive for efficient translation of current
EV research. On the basis of our in vitro an in vivo findings regarding the biological actions
of EVs and our experience in manufacturing biological stem cell therapeutics for routine use …
therapeutic effects that are comparable to their parental cells. MSC-EVs are promising
agents for the treatment of a variety of diseases. To reach the intermediate goal of clinically
testing safety and efficacy of EVs, strategies should strive for efficient translation of current
EV research. On the basis of our in vitro an in vivo findings regarding the biological actions
of EVs and our experience in manufacturing biological stem cell therapeutics for routine use …
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