Mapping genomic loci implicates genes and synaptic biology in schizophrenia

V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou… - Nature, 2022 - nature.com
genes implicated by such variants in neurodevelopmental disorders. We identify biological
processes relevant to schizophrenia … associations in schizophrenia and neurodevelopmental …

Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia

Schizophrenia Working Group of the Psychiatric … - MedRxiv, 2020 - medrxiv.org
… We show that genes we prioritise within associated loci by fine-mapping are highly enriched
… in schizophrenia, and identify GRIN2A, SP4, STAG1, and FAM120A as specific genes

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Indonesia Schizophrenia Consortium… - Nature, 2022 - research.vu.nl
genes implicated by such variants in neurodevelopmental disorders. We identify biological
processes relevant to schizophrenia … associations in schizophrenia and neurodevelopmental …

[HTML][HTML] Schizophrenia genomics: convergence on synaptic development, adult synaptic plasticity, or both?

J Hall, NJ Bray - Biological Psychiatry, 2022 - Elsevier
genes implicated in schizophrenia through genomic studies have reported roles in early
synapse … risk through exome sequencing and fine-mapping of GWAS loci have known roles in …

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

G Feng - 2022 - dspace.mit.edu
genes implicated by such variants in neurodevelopmental disorders. We identify biological
processes relevant to schizophrenia … associations in schizophrenia and neurodevelopmental …

Targeting synaptic plasticity in schizophrenia: insights from genomic studies

AW Mould, NA Hall, I Milosevic… - Trends in molecular …, 2021 - cell.com
genomic findings identify many hundreds of genomic loci … of SCZ and how they map onto
human neurodevelopment. The … robust changes in genes implicated in synaptic processes in …

[HTML][HTML] Mapping genomic loci implicates genes and synaptic biology in schizophrenia

E Sigurðsson, Indonesia Schizophrenia Consortium - 2022 - opinvisindi.is
genes implicated by such variants in neurodevelopmental disorders. We identify biological
processes relevant to schizophrenia … associations in schizophrenia and neurodevelopmental …

Genetic architecture of schizophrenia: a review of major advancements

SE Legge, ML Santoro, S Periyasamy… - Psychological …, 2021 - cambridge.org
… and rare genetic variants associated with schizophrenia in synaptic … identify new genetic
regions, improve fine-mapping to identify … Mapping genomic loci prioritises genes and implicates

[引用][C] Mapping genomic loci implicates genes and synaptic biology in schizophrenia

…, A de Jong, Indonesia Schizophrenia Consortium - Nature, 2022 - Nature Research

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

TH Pers, P Timshel, S Ripke, S Lent… - … molecular genetics, 2016 - academic.oup.com
… in the pre-synapse and synaptic vesicles also were enriched in the … criteria, we implicate
numerous gene sets and genes; in … After mapping gene symbols to Ensembl identifiers we were …