Markers of basal ganglia dysfunction and conversion to psychosis: neurocognitive deficits and dyskinesias in the prodromal period
BACKGROUND: Movement abnormalities and cognitive deficits may represent external
markers of an underlying neural process linked with the early etiology of psychosis. As basal
ganglia function plays a governing role in both movement and cognitive processes, an
understanding of the relationship between these phenomena stands to inform etiologic
conceptualizations of vulnerability and psychotic disorders. METHODS: In this investigation,
trained raters coded movement abnormalities in videotapes from structured interviews of …
markers of an underlying neural process linked with the early etiology of psychosis. As basal
ganglia function plays a governing role in both movement and cognitive processes, an
understanding of the relationship between these phenomena stands to inform etiologic
conceptualizations of vulnerability and psychotic disorders. METHODS: In this investigation,
trained raters coded movement abnormalities in videotapes from structured interviews of …
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