Mas-related G protein-coupled receptors offer potential new targets for pain therapy
The founding member of the Mas-related G-protein-coupled receptor (Mrgpr) family was
discovered in 1986. Since then, many more members of this receptor family have been
identified in multiple species, and their physiologic functions have been investigated widely.
Because they are expressed exclusively in small-diameter primary sensory neurons, the
roles of Mrgpr proteins in pain and itch have been best studied. This review will focus
specifically on the current knowledge of their roles in pathological pain and the potential …
discovered in 1986. Since then, many more members of this receptor family have been
identified in multiple species, and their physiologic functions have been investigated widely.
Because they are expressed exclusively in small-diameter primary sensory neurons, the
roles of Mrgpr proteins in pain and itch have been best studied. This review will focus
specifically on the current knowledge of their roles in pathological pain and the potential …
Mas-Related G-protein-Coupled Receptors Offer Potential New Targets for Pain Therapy
The founding member of the Mas-related G-protein-coupled receptor (Mrgpr) family was
discovered in 1986. Since then, many more members of this receptor family have been
identified in multiple species, and their physiologic functions have been investigated widely.
Because they are expressed exclusively in small-diameter primary sensory neurons, the
roles of Mrgpr proteins in pain and itch have been best studied. This review will focus
specifically on the current knowledge of their roles in pathological pain and the potential …
discovered in 1986. Since then, many more members of this receptor family have been
identified in multiple species, and their physiologic functions have been investigated widely.
Because they are expressed exclusively in small-diameter primary sensory neurons, the
roles of Mrgpr proteins in pain and itch have been best studied. This review will focus
specifically on the current knowledge of their roles in pathological pain and the potential …