Maternal PPARG Pro12Ala polymorphism is associated with infant's neurodevelopmental outcomes at 18 months of age
Background Peroxisome proliferator activated receptors (PPARs) are ligand activated
transcription factors with crucial functions in lipid homeostasis, glucose metabolism, anti-
inflammatory processes, placental development, and are involved in cognitive functions and
neurodegenerative diseases. Polymorphisms in PPAR genes are shown to influence the
activity of these receptors. Aims 1) To examine the association of PPARG Pro12Ala
polymorphism in pregnant women and their offspring on infant's neurodevelopmental …
transcription factors with crucial functions in lipid homeostasis, glucose metabolism, anti-
inflammatory processes, placental development, and are involved in cognitive functions and
neurodegenerative diseases. Polymorphisms in PPAR genes are shown to influence the
activity of these receptors. Aims 1) To examine the association of PPARG Pro12Ala
polymorphism in pregnant women and their offspring on infant's neurodevelopmental …
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