The cancer stem cell hypothesis states that tumors are heterogeneous and comprised of
several different cell types that have a range of reproductive potentials. Cancer stem cells
(CSCs), represent one class of cells that has both reproductive potential and the ability to
differentiate. These cells are thought to drive the progression of aggressive and recurring
cancers since they give rise to all other constituent cells within a tumor. With the
development of immunotherapy in the last decade, the specific targeting of CSCs has …