After the 1991 and 2003 Gulf war increased incidence of cancer especially (leukemia) in Babylon city which is a major motivation to measure the concentration of alpha particles in human blood. CR-39 using to measure the alpha particles emitted from radon concentration in thirty human blood samples for patients and healthy was collected from Morgan Hospital, Babylon, Iraq. The result is showed the highest concentrations in the blood sample for leukemia patient collected from centre city is 13.98±0.94 Bq/m 3. Whilst, the lowest concentration is collected from Al-Mudhatia 5.24±0.54 Bq/m 3 with an average value is 7.79±0.51 Bq/m 3. On the other hand, the concentration of alpha particles emitted from radon concentration in male blood samples higher than concentration in female blood samples. A negative correlation between the disease age and alpha particles concentration in human blood was found. The comparison shows that the concentration of alpha particles in the human blood samples in the present study is lower than the concentration of alpha particles reported by UNSCEAR (2000).