Global energy demand has been increasing exponentially in the last three decades, which has been exacerbated by climate change. To alleviate the energy load, researchers have been exploring innovative passive techniques to enhance the thermal performance of building envelopes. This research evaluates a novel building envelope solution, which includes the development of a Concrete Masonry Unit that is integrated with bio-based micro-encapsulated Phase Changing Materials. The mechanical behaviour of the enhanced CMU is investigated to study the applicability of PCMs into the no-slump concrete mix. Compatibility with the applicable standards opens a broader prospect for thermal characterization and building performance simulations of PCM enhanced CMU building envelopes.