Meta-analysis of genome-wide association studies of anxiety disorders

T Otowa, K Hek, M Lee, EM Byrne, SS Mirza… - Molecular …, 2016 - nature.com
genome-wide association analyses in nine samples of European ancestry from seven large,
independent studies. … the association between these phenotypes and genome-wide single …

Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders

W Li, R Chen, L Feng, X Dang, J Liu, T Chen… - Nature Human …, 2024 - nature.com
… limiting factor for genome-wide association studies (GWASs)) of individual studies can be …
a linear regression model was used for the genome-wide association analysis in the MVP, we …

A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders

C Rayner, JRI Coleman, KL Purves, J Hodsoll… - Translational …, 2019 - nature.com
genome-wide association meta-analyses of symptoms following cognitive behavioural therapy
in adults with anxiety disorders (n = … genome-wide association studies of complex traits. …

Meta-analysis of genome-wide association studies for panic disorder in the Japanese population

T Otowa, Y Kawamura, N Nishida, N Sugaya… - Translational …, 2012 - nature.com
… Panic disorder (PD) is a moderately heritable anxiety disordermeta-analysis of the two
genome-wide association studies (GWAS I and II). (a) Quantile–quantile plots of the association

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

BT Webb, AY Guo, BS Maher, Z Zhao… - European Journal of …, 2012 - nature.com
genome-wide association data for anxiety disorders. … Similarly, most existing genetic
association studies of ANX are limited … We used the genome scan meta-analysis (GSMA) …

Systematic review of genome-wide association studies of anxiety disorders and neuroticism

K van der Walt, M Campbell, DJ Stein… - The World Journal of …, 2023 - Taylor & Francis
genome wide association analyses)) AND ((anxiety disorder OR anxiety disorders) OR (anxiety
neurosis OR anxietyMeta-analysis of genome-wide association studies for neuroticism, …

44. GENOME-WIDE ASSOCIATION META-ANALYSIS OF ANXIETY SYMPTOMS IN 493,764 INDIVIDUALS

M Skelton, B Mitchell, E Assary, D Li… - European …, 2024 - Elsevier
… We identified 47 genome-wide significant loci in the meta-analysis. SNP heritability was
estimated as 5.5% (95% CI 5.0%-6.0%). Strong genetic correlations were estimated with Major …

Genome-wide and gene-based association studies of anxiety disorders in European and African American samples

T Otowa, BS Maher, SH Aggen, JL McClay… - PLoS …, 2014 - journals.plos.org
… To detect these loci, we performed genome-wide association studies (GWAS) of ADs. In …
trans-population gene-based meta-analysis did we detect significant association signals in three …

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

NR Wray, ML Pergadia, DHR Blackwood… - Molecular …, 2012 - nature.com
… gene association studies 10 have shown little consistency and hopes for new progress have
spurred on a generation of genome-wide association studies … of MDD or anxiety disorders. If …

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

M Nagel, PR Jansen, S Stringer, K Watanabe… - Nature …, 2018 - nature.com
… We annotated all of the SNPs in our genome-wide association (meta-)analyses to these …
one SNP in the neuroticism meta-analysis, the depression meta-analysis, the depressed affect …