of S. cerevisiae for production of the C4-dicarboxylic acids malate, succinate and fumarate.
These … In this thesis, we explore the use of the yeast Saccharomyces cerevisiae as a
metabolic engineering platform for production of the C4-dicarboxylic acids malate and
succinate. This familiar microorganism is not just a convenient model organism. Due to a
good tolerance to low pH and organic …