Metabolic labelling of cancer cells with glycodendrimers stimulate immune-mediated cytotoxicity
D Goyard, PI Diriwari, N Berthet - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
The recruitment of antibody naturally present in human blood stream at the surface of cancer
cells have been proved a promising immunotherapeutic strategy to fight cancer. Antibody
recruiting molecules (ARMs) combining tumor and antibody binding modules have been
developed for this purpose, however the formation of the interacting complex with both
antibody and cell is difficult to optimize to stimulate immune-mediated cytotoxicity. To
circumvent this limitation, we report herein a more direct approach combining cell …
cells have been proved a promising immunotherapeutic strategy to fight cancer. Antibody
recruiting molecules (ARMs) combining tumor and antibody binding modules have been
developed for this purpose, however the formation of the interacting complex with both
antibody and cell is difficult to optimize to stimulate immune-mediated cytotoxicity. To
circumvent this limitation, we report herein a more direct approach combining cell …
[引用][C] Metabolic labelling of cancer cells with glycodendrimers stimulate immunemediated cytotoxicity
N Berthet - Journée Scientifique du Médicament, 2023 - hal.science
Metabolic labelling of cancer cells with glycodendrimers stimulate immunemediated
cytotoxicity - Archive ouverte HAL …
cytotoxicity - Archive ouverte HAL …
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