Metastatic chromophobe renal cell carcinoma: presence or absence of sarcomatoid differentiation determines clinical course and treatment outcomes
Background Sarcomatoid features (SF) in renal cell carcinoma (RCC) denote poor
prognosis. Data for metastatic chromophobe RCC (ChRCC) with SF are limited. We studied
clinical outcomes and genomic features in this setting. Patients and Methods We performed
a retrospective review of newly diagnosed metastatic ChRCC patients; end points included
overall survival (OS), time to treatment failure (TTF), and time to metastatic recurrence (TTR)
after nephrectomy for localized disease. A subset of patients underwent next-generation …
prognosis. Data for metastatic chromophobe RCC (ChRCC) with SF are limited. We studied
clinical outcomes and genomic features in this setting. Patients and Methods We performed
a retrospective review of newly diagnosed metastatic ChRCC patients; end points included
overall survival (OS), time to treatment failure (TTF), and time to metastatic recurrence (TTR)
after nephrectomy for localized disease. A subset of patients underwent next-generation …
以上显示的是最相近的搜索结果。 查看全部搜索结果