… Metformin can be used either as initial therapy or as an … of metformin, which is now available
in the United States. … is not a major problem with metformin, and metformin is now used in …

… , including metformin, were synthesised and some (not metformin) … Metformin was rediscovered
in the search for antimalarial … the use of metformin to treat diabetes in 1957. However, …

… Metformin-based combination therapy is often superior to therapy with a single hypoglycemic
agent. The antihyperglycemic properties of metformin … action of metformin remains unclear, …

… Optimal metformin use requires clear understanding of its effects, … of metformin’s mechanism
of actionremainselusive, andthedrug’seffectsarelikelypleiotropic. For instance, metformin …

… In rats dosed with iv metformin, metformin … metformin and in this review we will primarily
focus on the liver and intestines, particularly when referring to the beneficial impact of metformin …

Metformin is a widely used biguanide drug due to its safety … of metformin were discovered,
and the benefits of metformin for … brief summary of the benefits of metformin and to discuss the …

… mechanisms of action of metformin, a potent … metformin on hepatic gluconeogenesis. The
demonstration that respiratory chain complex I, but not AMPK, is the primary target of metformin …

… may contribute more to the variations in the hepatic uptake and clinical effect of metformin. …
treated with metformin. We suggest that the mean plasma concentrations of metformin over a …

… Metformin does not stimulate insulin secretion and therefore is not associated with … control
with metformin does not induce weight gain and may cause weight loss. Metformin also has a …

… implications of metformin and discuss about the concerns in the use of metformin, referring
… We aimed here to review the new implications of metformin and discuss about the concerns …