[HTML][HTML] Methylation landscape of human breast cancer cells in response to dietary compound resveratrol

R Medina-Aguilar, C Pérez-Plasencia, LA Marchat… - PLoS …, 2016 - journals.plos.org
Aberrant DNA methylation is a frequent epigenetic alteration in cancer cells that has
emerged as a pivotal mechanism for tumorigenesis. Accordingly, novel therapies targeting
the epigenome are being explored with the aim to restore normal DNA methylation patterns
on oncogenes and tumor suppressor genes. A limited number of studies indicate that dietary
compound resveratrol modulates DNA methylation of several cancer-related genes;
however a complete view of changes in methylome by resveratrol has not been reported yet …

[PDF][PDF] Methylation landscape of human breast cancer cells in response to dietary compound resveratrol

LAM MARCHAU - 2016 - rdcb.cbg.ipn.mx
Aberrant DNA methylation is a frequent epigenetic alteration in cancer cells that has
emerged as a pivotal mechanism for tumorigenesis. Accordingly, novel therapies targeting
the epigenome are being explored with the aim to restore normal DNA methylation patterns
on oncogenes and tumor suppressor genes. A limited number of studies indicate that dietary
compound resveratrol modulates DNA methylation of several cancer-related genes;
however a complete view of changes in methylome by resveratrol has not been reported yet …
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