Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid …

E Janecek, E Wilk, K Schughart, R Geffers… - International Journal for …, 2015 - Elsevier
Toxocara canis and Toxocara cati are globally occurring intestinal nematodes of dogs and
cats with a high zoonotic potential. Migrating larvae in the CNS of paratenic hosts, including
humans, may cause neurotoxocarosis resulting in a variety of neurological symptoms.
Toxocara canis exhibits a stronger affinity to the CNS than T. cati, causing more severe
neurological symptoms in the mouse model. Pathomechanisms of neurotoxocarosis as well
as host responses towards the respective parasite are mostly unknown. Therefore, the aim …
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