Mid-pregnancy maternal blood nitric oxide-related gene and miRNA expression are associated with preterm birth

TA Manuck, LA Eaves, JE Rager, RC Fry - Epigenomics, 2021 - Taylor & Francis
Aim: The nitric oxide (NO) pathway modulates inflammation and may influence birth timing.
Patients & methods: Case–control analysis of 136 pregnant women with RNA obtained<
28Â weeks; nÂ= Â 212 mRNAs and nÂ= Â 108 miRNAs in the NO pathway were evaluated.
NO-pathway mRNA and miRNA transcript counts in women delivering preterm versus at
term were compared, miRNA–mRNA expression levels correlated and prediction models
generated. Results: Fourteen genes were differentially expressed in women delivering< 37 …

[引用][C] Mid-pregnancy maternal blood nitric oxide-related gene and miRNA expression are associated with preterm birth. Epigenomics. 2021; 13 (9): 667–82

TA Manuck, LA Eaves, JE Rager, RC Fry
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