The most difficult challenge in the world is widespread access to good and healthful food. For the human diet, vegetables are considered as a crucial element and are regarded as natural nutritional reserves. Heavy metals are threatening dietary contaminants, and their consumption causes a variety of health problems. In urban and peri-urban regions people utilize wastewater, particularly sewage effluent, to irrigate agricultural fields because of the scarcity of fresh water. Nevertheless, there is growing worry about the possible health concerns linked with consuming tainted veggies. This scenario is especially concerning in vegetables cultivated in industrial locations, which have a high prevalence of heavy metal build-up. As a result, a research project was launched to determine the long duration impact of polluted water irrigation on concentrations of heavy metals (HMs) in soil and vegetable crops. In soil, vegetable and water samples, a high concentration of Lead and Cadmium was found. In this study, heavy metals were reduced in spinach and kale obtained from peri-urban locations by treating them with various biochemical adsorbent solutions. Using an Atomic Absorption Spectrophotometer (AAS), the amount of heavy metals in soil, vegetable and water samples was evaluated. To find the most effective adsorption therapy for HM's mitigation, the data was statistically analysed. Treatment with several biochemical adsorbent solutions resulted in a considerable decrease in heavy metal concentration. Among various chemical adsorbents, 15% sodium carbonate proved maximum reduction potential and among various biological adsorbents, 15 % orange peel extract proved maximum reduction potential for HMs eradication off vegetable sampling.