Modeling growth factor activity during proinflammatory stress: Methodological considerations in assessing cytokine modulation of IGF binding proteins released by …
TH Elsasser, TJ Caperna, PJ Ward, JL Sartin… - Domestic animal …, 2007 - Elsevier
The present research was conducted to model potential mechanisms through which IGFBPs
might be affected by a key proinflammatory response initiating cytokine tumor necrosis factor
(TNF-)-α. Madin–Darby bovine kidney epithelial (MDBK) cells, known to release IGFBPs in
response to several stimuli, were grown under several conditions and challenged with
forskolin (F) or recombinant TNF-α for 24h. Forskolin increased IGFBP-3 gene expression
and media content of BP-3 protein. TNF-α increased basal and augmented F-mediated …
might be affected by a key proinflammatory response initiating cytokine tumor necrosis factor
(TNF-)-α. Madin–Darby bovine kidney epithelial (MDBK) cells, known to release IGFBPs in
response to several stimuli, were grown under several conditions and challenged with
forskolin (F) or recombinant TNF-α for 24h. Forskolin increased IGFBP-3 gene expression
and media content of BP-3 protein. TNF-α increased basal and augmented F-mediated …
以上显示的是最相近的搜索结果。 查看全部搜索结果