Modulation of microRNAs as a potential molecular mechanism involved in the beneficial actions of physical exercise in Alzheimer disease
AC Improta-Caria, CKV Nonaka… - International journal of …, 2020 - mdpi.com
Alzheimer disease (AD) is one of the most common neurodegenerative diseases, affecting
middle-aged and elderly individuals worldwide. AD pathophysiology involves the
accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, along with
chronic neuroinflammation and neurodegeneration. Physical exercise (PE) is a beneficial
non-pharmacological strategy and has been described as an ally to combat cognitive
decline in individuals with AD. However, the molecular mechanisms that govern the …
middle-aged and elderly individuals worldwide. AD pathophysiology involves the
accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, along with
chronic neuroinflammation and neurodegeneration. Physical exercise (PE) is a beneficial
non-pharmacological strategy and has been described as an ally to combat cognitive
decline in individuals with AD. However, the molecular mechanisms that govern the …
Modulation of MicroRNAs as a Potential Molecular Mechanism Involved in the Beneficial Actions of Physical Exercise in Alzheimer Disease
Alzheimer disease (AD) is one of the most common neurodegenerative diseases, a ecting
middle-aged and elderly individuals worldwide. AD pathophysiology involves the
accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, along with
chronic neuroinflammation and neurodegeneration. Physical exercise (PE) is a beneficial
non-pharmacological strategy and has been described as an ally to combat cognitive
decline in individuals with AD. However, the molecular mechanisms that govern the …
middle-aged and elderly individuals worldwide. AD pathophysiology involves the
accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, along with
chronic neuroinflammation and neurodegeneration. Physical exercise (PE) is a beneficial
non-pharmacological strategy and has been described as an ally to combat cognitive
decline in individuals with AD. However, the molecular mechanisms that govern the …
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