Purpose Management of Retinoblastoma (RB), a pediatric ocular cancer is limited by drug-
resistance and drug-dosage related side effects during chemotherapy. Molecular de-
regulation in post-chemotherapy RB tumors was investigated. Materials and Methods cDNA
microarray analysis of two post-chemotherapy and one pre-chemotherapy RB tumor tissues
was performed, followed by Principle Component Analysis, Gene ontology, Pathway
Enrichment analysis and Biological Analysis Network (BAN) modeling. The drug modulation …

Molecular Insights on Post-chemotherapy Retinoblastoma by Microarray Gene Expression
Analysis … Management of Retinoblastoma (RB), a pediatric ocular cancer is limited by
drug-resistance and drug-dosage related side effects during chemotherapy. Molecular de-regulation
in post-chemotherapy RB tumors was investigated. …