Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann, K Mai… - Journal of Experimental …, 2022 - rupress.org
Using this AAV animal model, we demonstrate a role of cGAS/STING/IRF3 pathway in …
between lung macrophages whereby recruited monocyte-derived macrophages promoted …

Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway

YL Chen, CC Yang, YS Miao, DC Shi, X Li… - Nature …, 2025 - nature.com
… with lungpulmonary fibrosis, liver fibrosis, and renal fibrosis 13,14,15 . STING is highly
expressed on haematopoietic cells, such as macrophages 16 ,and the presence of macrophages

Macrophage STING signaling promotes fibrosis in benign airway stenosis via IL6-STAT3 axis

H Shi, YL Chen, CC Yang, YS Miao, DC Shi, X Li… - 2024 - researchsquare.com
… We determined that the cGAS-STING pathway in macrophages is critical in … Monocyte-derived
macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic

Correction: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N Kessler, SF Viehmann, C Krollmann, K Mai… - Journal of Experimental …, 2022 - rupress.org
vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing | Journal of … : Monocyte-derived
macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid …

Correction: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing Nina Kessler, Susanne F. Viehmann …

CK Heeringa, N Garbi - 2022 - minerva-access.unimelb.edu.au
The authors regret that Figs. 1, 3, and 5 contained errors in the original version of their article.
In Fig. 1 C, the color-coded diagnosis legend indicating MPO (dark yellow) or control (dark …

A novel STING variant triggers endothelial toxicity and SAVI disease

E Valeri, S Breggion, F Barzaghi… - Journal of Experimental …, 2024 - rupress.org
… ), is a cytosolic nucleic acid sensor that plays a central … macrophages has been reported
as a key driver of severe ANCA-associated vasculitis leading to endothelial damage, pulmonary

Single-cell RNA-sequencing of PBMCs from SAVI patients reveals disease-associated monocytes with elevated integrated stress response

C de Cevins, L Delage, M Batignes, Q Riller… - Cell Reports …, 2023 - cell.com
… is thought to be the leading cause of the symptoms observed in patients… by severe pulmonary
and cutaneous manifestations. … The STING pathway acts as a sensor of cytoplasmic nucleic

Silencing HOXC13 exerts anti-prostate cancer effects by inducing DNA damage and activating cGAS/STING/IRF3 pathway

M Li, G Bai, Y Cen, Q Xie, J Chen, J Chen… - Journal of Translational …, 2023 - Springer
… system and the second leading cause of cancer death in men [… We performed a reliable
immunoscoring assessment using … differentiate into macrophages, of which M2 macrophages are …

Innate Immune Response to Viral Vectors in Gene Therapy

Y Wang, W Shao - Viruses, 2023 - mdpi.com
… Notably, conventional dendritic cells and macrophages elicit … of lung cancer, the delivery
of rAd-p53 and IL-2 using an … , as well as the delivered nucleic acid sequences, can trigger …

[HTML][HTML] Opposing roles of resident and infiltrating immune cells in the defence against Legionella longbeachae via IL-18R/IFN-γ/ROS axis in mice

LM Oberkircher, VM Scheiding, HL Rafeld… - Mucosal …, 2024 - Elsevier
… an influx of neutrophils and later monocyte-derived cells (MC) into lung tissue. AM carried
greater … using murine bone marrow-derived macrophages have suggested that macrophages