… hepatitis B virus (HBV). However, we recently demonstrated that monotherapy with tenofovir
disoproxil fumarate (… therapy in patients with HBV resistant to multiple drugs, including ETV …

… with chronic HBV infection with resistance to antivirals from 8 tertiary hospitals in Korea. Patients
(n=423) received rescue therapy with TDF monotherapy (n… HBV DNA level of <20 IU/mL. …

… patients who have HBV resistant to multiple NUCs, such as … that tenofovir disoproxil fumarate
(TDF) monotherapy provides … who acquired multiple HBV mutations resistant to ETV and/or …

… DNA levels >60 IU/mL were randomised to receive tenofovir disoproxil fumarate (TDF, 300
… mutants.12 ,13 However, many patients worldwide have developed drug resistance from the …

… The availability of potent NUCs, such as entecavir (ETV) and tenofovir disoproxil fumarate
(TDF), which have a minimal risk of drug resistance, has enabled reduction of serum HBV …

… 48 weeks of tenofovir disoproxil fumarate (TDF) monotherapy had … with HBV resistant to
ETV and/or ADV. In the subsequent … most patients with multidrug-resistant HBV could achieve …

… The treatment of multidrug-resistant (MDR) chronic hepatitis B (… study for the evaluation of
tenofovir disoproxil fumarate (TDF)-based … Antiviral responses according to drug resistance. A, …

… Tenofovir disoproxil fumarate (TDF) monotherapy is a … TDF alone (monotherapy group) or
TDF combined with LAM or … variants with substitutions conferring antiviral drug resistance, was …

… tenofovir disoproxil fumarate treatment at 300 mg once a day for at least 48 weeks and as
monotherapy for chronic hepatitis … meet multiple eligibility criteria. Two patients assigned to the …

… we investigated the efficacy of tenofovir disoproxil fumarate (TDF) … with CHB exhibiting antiviral
drug resistance treated by TDF … However, long-term LAM monotherapy is associated with …