Mood disorders and biological rhythms in young adults: a large population-based study
TC Mondin, T de Azevedo Cardoso… - Journal of psychiatric …, 2017 - Elsevier
Journal of psychiatric research, 2017•Elsevier
Background It is known that sleep disturbance has been considered a trait-marker of mood
disorders. However, the role of disruptions in biological rhythms, such as eating, activity, and
social patterns, needs to be better understood. Aim To assess the differences in biological
rhythms in subjects with bipolar disorder, major depressive disorder, and healthy controls.
We also tested the association between disruptions of biological rhythms and circadian
preferences. Methods A cross-sectional, population-based study with a representative …
disorders. However, the role of disruptions in biological rhythms, such as eating, activity, and
social patterns, needs to be better understood. Aim To assess the differences in biological
rhythms in subjects with bipolar disorder, major depressive disorder, and healthy controls.
We also tested the association between disruptions of biological rhythms and circadian
preferences. Methods A cross-sectional, population-based study with a representative …
Background
It is known that sleep disturbance has been considered a trait-marker of mood disorders. However, the role of disruptions in biological rhythms, such as eating, activity, and social patterns, needs to be better understood.
Aim
To assess the differences in biological rhythms in subjects with bipolar disorder, major depressive disorder, and healthy controls. We also tested the association between disruptions of biological rhythms and circadian preferences.
Methods
A cross-sectional, population-based study with a representative sample of 1023 young adults. Bipolar disorder and depression were diagnosed using The Mini International Neuropsychiatric Interview – PLUS and DSM Structured Clinical Interview. Self-reported biological rhythms and circadian preference were assessed using the Biological Rhythm Interview of Assessment in Neuropsychiatry (BRIAN).
Results
Bipolar disorders and depression subjects presented higher rates of disruption in biological rhythms when compared to healthy controls even after adjusting for sex, socioeconomic status, alcohol, tobacco, illicit drug use, anxiety disorder and psychotropic medication use. Euthymic subjects showed higher biological rhythm disruption when compared to controls. Higher disruption in biological rhythms was observed in subjects with evening preferences.
Conclusion
Higher disruption in biological rhythms occurs in individuals with depression and bipolar disorder even on periods of euthymia.
Elsevier
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